Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880778 | 1.00 | ALOX15 (0.51) | ALOX15HTTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL17631647 | 0.83 | ALOX15 (0.50) | ALOX15HTTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL30523282 | 0.83 | ALOX15 (0.50) | ALOX15HTTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL1594540 | 0.83 | HTT (0.50) | ALOX15HTTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL15553325 | 0.83 | ALOX15 (0.50) | ALOX15HTTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL1601229 | 0.81 | CYP2A6 (0.50) | KDM4EHPGDPSMD14CYP1A2CYP2A6 | |
| SCHEMBL2671631 | 0.81 | ALOX15 (0.49) | ALOX15HTTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL19296076 | 0.81 | PLAU (0.51) | PSMD14CYP1A2CYP2A6 | |
| SCHEMBL709231 | 0.80 | LCK (0.62) | ALOX15HTTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL15512057 | 0.80 | ROCK1 (0.47) | ALOX15HTTCYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301127-A | 6-Oxo-decahydro pyrrolo [1,2-a ] [1,5] diazocine and 6-oxo-decahydro-4H-pyrrolo [2,1-d ] [1,5] thiaazacine derivatives as modulators of STAT3 and STAT6 for the treatment of cancer and inflammatory conditions | 瑞克鲁迪克斯制药股份有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-118804917-A | STAT modulators and uses thereof | 瑞克鲁迪克斯制药股份有限公司 | 2024-10-18 | — | — | CN | disclosed |