Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | HRH2 | P25021 | 4/20 | 0.47 |
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31250707 | 0.93 | CA1 (0.51) | CTSKHRH2HRH1KCNA3CA1 | |
| SCHEMBL7578857 | 0.92 | KCNA3 (0.52) | CTSKHRH2HRH1KCNA3CA1 | |
| SCHEMBL31250540 | 0.89 | CTSK (0.48) | CTSKHRH2HRH1KCNA3CA1 | |
| SCHEMBL31665575 | 0.89 | KCNA3 (0.51) | CTSKKCNA3CA1CA2HSD11B1 | |
| SCHEMBL31250722 | 0.89 | CTSK (0.52) | CTSKHRH2HRH1KCNA3CA1 | |
| SCHEMBL24001253 | 0.88 | KCNA3 (0.50) | CTSKKCNA3CA1CA2HSD11B1 | |
| SCHEMBL13583442 | 0.86 | CTSK (0.54) | CTSKHRH2HRH1KCNA3CA1 | |
| SCHEMBL13583443 | 0.86 | CTSK (0.54) | CTSKHRH2HRH1KCNA3CA1 | |
| SCHEMBL21584005 | 0.85 | CTSK (0.53) | CTSKHRH2HRH1KCNA3CA1 | |
| SCHEMBL24036902 | 0.85 | CTSK (0.53) | CTSKHRH2HRH1KCNA3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720058-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | Casma Therapeutics, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249291-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | CASMA THERAPEUTICS, INC. (US) | 2024-12-05 | — | — | WO | disclosed |