Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 10/20 | 0.39 |
| ▸ | CTSS | P25774 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648146 | 0.92 | CYP2D6 (0.47) | CYP2D6CA2CA1CA7ATM | |
| SCHEMBL28648145 | 0.92 | CYP2D6 (0.47) | CYP2D6CA2CA1CA7ATM | |
| SCHEMBL19544923 | 0.89 | TSHR (0.42) | CYP2D6CA2CA1CA7ATM | |
| SCHEMBL29265449 | 0.89 | CA1 (0.42) | CYP2D6CA2CA1CA7ATM | |
| SCHEMBL30422267 | 0.89 | CA1 (0.42) | CYP2D6CA2CA1CA7ATM | |
| SCHEMBL26501084 | 0.87 | CYP1A2 (0.47) | CYP2D6CTSKCTSSKMT2A | |
| SCHEMBL19412345 | 0.86 | CA1 (0.41) | CYP2D6CA2CA1CA7ATM | |
| SCHEMBL19412348 | 0.86 | CA1 (0.41) | CYP2D6CA2CA1CA7ATM | |
| SCHEMBL11126899 | 0.86 | CYP2D6 (0.45) | CYP2D6CA2CA1CA7ATM | |
| SCHEMBL11126904 | 0.86 | CYP2D6 (0.45) | CYP2D6CA2CA1CA7ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720058-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | Casma Therapeutics, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249291-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | CASMA THERAPEUTICS, INC. (US) | 2024-12-05 | — | — | WO | disclosed |