Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 12/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19412348 | 1.00 | CA1 (0.41) | CA1CA2CA7CTSKATM | |
| SCHEMBL30422267 | 0.90 | CA1 (0.42) | CA1CA2CA7CTSKATM | |
| SCHEMBL29265449 | 0.90 | CA1 (0.42) | CA1CA2CA7CTSKATM | |
| SCHEMBL28648146 | 0.88 | CYP2D6 (0.47) | CA1CA2CA7CTSKATM | |
| SCHEMBL28648145 | 0.88 | CYP2D6 (0.47) | CA1CA2CA7CTSKATM | |
| SCHEMBL29402441 | 0.86 | CTSK (0.42) | CA1CA2CA7CTSKATM | |
| SCHEMBL14265314 | 0.86 | CTSK (0.42) | CA1CA2CA7CTSKATM | |
| SCHEMBL31251011 | 0.86 | CYP2D6 (0.42) | CA1CA2CA7CTSKATM | |
| SCHEMBL3830098 | 0.85 | CTSK (0.41) | CA1CA2CA7CTSKATM | |
| SCHEMBL6684772 | 0.85 | CA1 (0.49) | CA1CA2CA7CTSKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436007-A1 | BETA-AMIMO PATEAMINE A DERIVATIVES AND METHODS FOR TREATING CHRONIC LYMPHOCYTIC LEUKEMIA | The Texas A&M University System (US) | 2019-02-06 | — | — | EP | disclosed |
| WO-2017173313-A1 | BETA-AMIMO PATEAMINE A DERIVATIVES AND METHODS FOR TREATING CHRONIC LYMPHOCYTIC LEUKEMIA | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-10-05 | — | — | WO | disclosed |