SCHEMBL31251286

SCHEMBL31251286

COCC1(NCc2cc(C(F)(F)F)c3ncc(-c4cccc(C5(c6nncn6C)CC(C)C5)c4)c(=O)n3c2)CC1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.67
▸ CBLC Q9ULV8 2/20 0.57
▸ CBL P22681 16/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26486416 0.89 CBLB (0.71) CBLBCBLCCBL
SCHEMBL31251432 0.89 CBLB (0.69) CBLBCBLCCBL
SCHEMBL31251177 0.87 CBLB (0.67) CBLBCBLCCBL
SCHEMBL31251204 0.87 CBLB (0.67) CBLBCBLCCBL
SCHEMBL31251484 0.86 CBLB (0.67) CBLBCBLCCBL
SCHEMBL31251296 0.86 CBLB (0.76) CBLBCBLCCBL
SCHEMBL31251410 0.85 CBLB (0.72) CBLBCBLCCBL
SCHEMBL31251309 0.85 CBLB (0.67) CBLBCBLCCBL
SCHEMBL26480500 0.85 CBLB (0.67) CBLBCBLCCBL
SCHEMBL26480594 0.83 CBLB (0.80) CBLBCBLCCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024245264-A1 CBL-B INHIBITOR AND USE THEREOF 海南先声再明医药股份有限公司 2024-12-05 — — WO disclosed
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