SCHEMBL31251309

SCHEMBL31251309

CC1CC(c2cccc(-c3cnc4c(C(F)(F)F)cc(CNCC5(O)CCC5)cn4c3=O)c2)(c2nncn2C)C1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.67
▸ CBL P22681 16/20 0.53
▸ CBLC Q9ULV8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31251204 0.90 CBLB (0.67) CBLBCBLCBLC
SCHEMBL26486416 0.89 CBLB (0.71) CBLBCBLCBLC
SCHEMBL31251432 0.87 CBLB (0.69) CBLBCBLCBLC
SCHEMBL31251484 0.86 CBLB (0.67) CBLBCBLCBLC
SCHEMBL31251296 0.86 CBLB (0.76) CBLBCBLCBLC
SCHEMBL26480500 0.85 CBLB (0.67) CBLBCBLCBLC
SCHEMBL31251286 0.85 CBLB (0.67) CBLBCBLCBLC
SCHEMBL31251177 0.83 CBLB (0.67) CBLBCBLCBLC
SCHEMBL31251410 0.83 CBLB (0.72) CBLBCBLCBLC
SCHEMBL26480594 0.83 CBLB (0.80) CBLBCBLCBLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024245264-A1 CBL-B INHIBITOR AND USE THEREOF 海南先声再明医药股份有限公司 2024-12-05 — — WO disclosed
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