Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 17/20 | 0.40 |
| ▸ | WDR48 | Q8TAF3 | 13/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31155879 | 0.84 | USP1 (0.51) | USP1WDR48 | |
| SCHEMBL31254619 | 0.84 | USP1 (0.37) | USP1WDR48ALDH1A1GAA | |
| SCHEMBL31138614 | 0.80 | USP1 (0.35) | USP1WDR48 | |
| SCHEMBL31254876 | 0.80 | USP1 (0.59) | USP1WDR48 | |
| SCHEMBL31254707 | 0.77 | USP1 (0.45) | USP1 | |
| SCHEMBL31138705 | 0.76 | USP1 (0.37) | USP1WDR48 | |
| SCHEMBL31138473 | 0.76 | USP1 (0.40) | USP1WDR48RXRAGRIN1GRIN2B | |
| SCHEMBL31254883 | 0.76 | USP1 (0.43) | USP1WDR48 | |
| SCHEMBL31254943 | 0.75 | USP1 (0.44) | USP1WDR48 | |
| SCHEMBL31254615 | 0.73 | USP1 (0.48) | USP1WDR48RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233665-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |