Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 11/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31254911 | 0.90 | USP1 (0.43) | USP1HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL31255089 | 0.86 | USP1 (0.42) | USP1HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL31254682 | 0.86 | USP1 (0.42) | USP1HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL31254650 | 0.86 | USP1 (0.49) | USP1 | |
| SCHEMBL31254921 | 0.86 | USP1 (0.41) | USP1HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL31254707 | 0.85 | USP1 (0.45) | USP1HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL31254760 | 0.81 | USP1 (0.40) | USP1HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL31254810 | 0.80 | USP1 (0.40) | USP1HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL31138370 | 0.80 | USP1 (0.39) | USP1HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL31254597 | 0.78 | USP1 (0.50) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233665-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |