SCHEMBL31254953

SCHEMBL31254953

[2H]C([2H])([2H])Oc1cnc(Cl)nc1OCc1ccc(-c2nc(C(F)(F)F)cn2C)cc1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.45
▸ WDR48 Q8TAF3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31155920 0.93 USP1 (0.51) USP1WDR48
SCHEMBL31255009 0.90 USP1 (0.45) USP1WDR48
SCHEMBL31254712 0.89 USP1 (0.45) USP1WDR48
SCHEMBL31254671 0.88 USP1 (0.45) USP1
SCHEMBL31255115 0.88 USP1 (0.45) USP1
SCHEMBL31254788 0.88 USP1 (0.45) USP1
SCHEMBL31254755 0.87 USP1 (0.48) USP1
SCHEMBL31254791 0.87 USP1 (0.44) USP1
SCHEMBL31155911 0.86 USP1 (0.43) USP1
SCHEMBL31155857 0.86 USP1 (0.47) USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233665-A1 COMPOUNDS AND THEIR USE AGAINST CANCER TANGO THERAPEUTICS, INC. (US) 2024-11-14 — — WO disclosed
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