SCHEMBL31255063

SCHEMBL31255063

COc1cnc(-c2c(OC(F)F)ncnc2C2CC2)nc1OCc1cnc(-c2nc(C(F)(F)F)cn2C2CC2)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.50
▸ WDR48 Q8TAF3 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31254715 0.94 USP1 (0.56) USP1WDR48
SCHEMBL31254832 0.91 USP1 (0.52) USP1WDR48
SCHEMBL31254991 0.91 USP1 (0.54) USP1WDR48
SCHEMBL31254815 0.90 USP1 (0.53) USP1WDR48
SCHEMBL31254554 0.88 USP1 (0.62) USP1WDR48
SCHEMBL31254610 0.87 USP1 (0.57) USP1WDR48
SCHEMBL31255034 0.86 USP1 (0.57) USP1WDR48
SCHEMBL31138723 0.85 USP1 (0.44) USP1WDR48
SCHEMBL31255016 0.85 USP1 (0.59) USP1WDR48
SCHEMBL31254876 0.84 USP1 (0.59) USP1WDR48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233665-A1 COMPOUNDS AND THEIR USE AGAINST CANCER TANGO THERAPEUTICS, INC. (US) 2024-11-14 — — WO disclosed
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