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SCHEMBL31256982

SCHEMBL31256982

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CCC(N)=O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 16/20 0.60
▸ NPY1R P25929 10/20 0.60
▸ NPY5R Q15761 9/20 0.60
▸ NPY2R P49146 6/20 0.60
▸ CD40 P25942 1/20 0.49
▸ TFPI P10646 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31013834 0.94 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30354440 0.94 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL29679826 0.93 NPY4R (0.51) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL29376109 0.92 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL29375535 0.92 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL29376626 0.91 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29851196 0.91 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2RCD40
SCHEMBL29679795 0.91 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29373534 0.90 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29679932 0.90 NPY4R (0.49) NPY4RNPY1RNPY5RNPY2RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240352445-A1 HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES ABWIZ BIO, INC. 2024-10-24 — — US disclosed
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