Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 6/20 | 0.45 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 2/20 | 0.41 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31281377 | 0.83 | CALCRL (0.51) | CAPN1CALCRLRAMP1XIAPSLC6A2 | |
| SCHEMBL22546193 | 0.82 | XIAP (0.49) | CAPN1XIAPCTSBSLC6A2ELANE | |
| SCHEMBL30139053 | 0.80 | CAPN1 (0.42) | CAPN1SLC6A2 | |
| SCHEMBL30974101 | 0.80 | CALCRL (0.46) | CALCRL | |
| SCHEMBL30284980 | 0.80 | CALCRL (0.46) | CAPN1CALCRLRAMP1XIAPMLX | |
| SCHEMBL31495942 | 0.79 | CALCRL (0.43) | CAPN1CALCRLRAMP1XIAPMLX | |
| SCHEMBL29689606 | 0.79 | XIAP (0.53) | XIAPELANE | |
| SCHEMBL31562168 | 0.79 | XIAP (0.43) | CAPN1CALCRLRAMP1XIAPMLX | |
| SCHEMBL29473879 | 0.79 | CAPN1 (0.51) | CAPN1CTSB | |
| SCHEMBL30054357 | 0.79 | CALCRL (0.41) | CAPN1CALCRLRAMP1XIAPMLX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240352445-A1 | HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES | ABWIZ BIO, INC. | 2024-10-24 | — | — | US | disclosed |