Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PLAU | P00749 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 4/20 | 0.55 |
| ▸ | CCND1 | P24385 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844137 | 1.00 | HTR6 (0.70) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL31021 | 0.85 | HTR6 (0.73) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL29509279 | 0.85 | HTR6 (0.73) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL6085996 | 0.84 | HTR6 (0.58) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL31257980 | 0.84 | HTR6 (0.58) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL2247137 | 0.84 | HTR6 (0.72) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL29459650 | 0.84 | HTR6 (0.72) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL6087734 | 0.82 | HTR6 (0.70) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL6085799 | 0.82 | HTR6 (0.70) | HTR6KMT2APLAUHDAC1HDAC2 | |
| SCHEMBL21335591 | 0.82 | HTR6 (0.70) | HTR6KMT2APLAUHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119080667-A | Aminoguanidine indole derivative and preparation method and application thereof | 中国农业科学院兰州畜牧与兽药研究所 | 2024-12-06 | — | — | CN | claimed |
| CN-119080667-A | Aminoguanidine indole derivative and preparation method and application thereof | 中国农业科学院兰州畜牧与兽药研究所 | 2024-12-06 | — | — | CN | disclosed |