Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 5/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 7/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31258476 | 0.85 | PIK3CD (0.37) | EPHA2EPHB4KDRERBB2PIK3CD | |
| SCHEMBL30264691 | 0.79 | EPHA2 (0.46) | ENPP1EPHA2EPHB4KDRERBB2 | |
| SCHEMBL30639974 | 0.77 | ERBB2 (0.49) | ENPP1EPHA2EPHB4KDRERBB2 | |
| SCHEMBL31377604 | 0.77 | ERBB2 (0.49) | ENPP1EPHA2EPHB4KDRERBB2 | |
| SCHEMBL30639977 | 0.77 | ERBB2 (0.49) | ENPP1EPHA2EPHB4KDRERBB2 | |
| SCHEMBL665187 | 0.76 | PIK3CD (0.54) | EPHA2EPHB4KDRERBB2PIK3CD | |
| SCHEMBL29465791 | 0.76 | PIK3CD (0.54) | EPHA2EPHB4KDRERBB2PIK3CD | |
| SCHEMBL29465790 | 0.76 | PIK3CD (0.54) | EPHA2EPHB4KDRERBB2PIK3CD | |
| SCHEMBL2453138 | 0.76 | PIK3CD (0.54) | EPHA2EPHB4KDRERBB2PIK3CD | |
| SCHEMBL22598590 | 0.75 | PIK3CD (0.51) | ENPP1EHMT2EPHA2EPHB4ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715216-A | Nitrogen-containing heterocyclic compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-09-27 | — | — | CN | disclosed |