Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.31 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31258474 | 0.85 | ENPP1 (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGEPHA2 | |
| SCHEMBL26111113 | 0.75 | GPR119 (0.49) | PIK3CDIRAK4GPR119 | |
| SCHEMBL30639958 | 0.75 | GPR119 (0.49) | PIK3CDIRAK4GPR119 | |
| SCHEMBL30140141 | 0.72 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL30264691 | 0.70 | EPHA2 (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL30127386 | 0.69 | HPGDS (0.45) | PIK3CDIRAK4PIK3CAPIK3CBPIK3CG | |
| SCHEMBL28983490 | 0.68 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL1074518 | 0.67 | DDB1 (0.33) | GPR119POLB | |
| SCHEMBL31377604 | 0.67 | ERBB2 (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 | |
| SCHEMBL30639974 | 0.67 | ERBB2 (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715216-A | Nitrogen-containing heterocyclic compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-09-27 | — | — | CN | disclosed |