SCHEMBL31258508

SCHEMBL31258508

COC(=O)c1cc(C)n2nccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
GAA P10253 2/20 0.40
RAB9A P51151 1/20 0.40
POLB P06746 2/20 0.40
XDH P47989 2/20 0.40
LMNA P02545 1/20 0.40
NFKB1 P19838 1/20 0.40
GFER P55789 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
FUT7 Q11130 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31258504 1.00 KDM4E (0.41) KDM4EALDH1A1TDP1CA12CA1
SCHEMBL31258497 0.85 CA12 (0.46) KDM4EALDH1A1CA12CA1CA2
SCHEMBL31258494 0.85 CA12 (0.46) KDM4EALDH1A1CA12CA1CA2
SCHEMBL25237230 0.83 KDM4E (0.40) KDM4EALDH1A1TDP1CA12CA1
SCHEMBL25785935 0.81 PARP1 (0.37) KDM4EALDH1A1LMNAMAPK1KDM4C
SCHEMBL3642134 0.73 JMJD6 (0.44) KDM4EALDH1A1CA12CA1CA2
SCHEMBL31258511 0.73 GRM4 (0.53) ALDH1A1RAB9ALMNA
SCHEMBL31258513 0.73 GRM4 (0.53) ALDH1A1RAB9ALMNA
SCHEMBL351584 0.72 KDM4E (0.46) KDM4EALDH1A1LMNAMAPK1HPGD
SCHEMBL17331592 0.70 ALDH1A1 (0.47) KDM4EALDH1A1TDP1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695247-A1 PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES Syngenta Crop Protection AG (CH) 2026-02-18 EP disclosed
WO-2024213662-A1 PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 WO disclosed