Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18423997 | 1.00 | HDAC6 (0.51) | HDAC6 | |
| SCHEMBL30424795 | 0.89 | HDAC6 (0.48) | HDAC6 | |
| SCHEMBL26227321 | 0.86 | ALOX12 (0.50) | HDAC6 | |
| SCHEMBL24011440 | 0.85 | LRRK2 (0.43) | HDAC6 | |
| SCHEMBL26529933 | 0.84 | HDAC6 (0.55) | HDAC6 | |
| SCHEMBL14804388 | 0.82 | NPC1 (0.53) | — | |
| SCHEMBL22116720 | 0.82 | HDAC6 (0.51) | HDAC6 | |
| SCHEMBL25431225 | 0.81 | HDAC6 (0.56) | HDAC6 | |
| SCHEMBL22116954 | 0.81 | NPC1 (0.59) | HDAC6 | |
| SCHEMBL22116982 | 0.81 | HDAC6 (0.50) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171433-A1 | A1H-BENZO[C][1,2]THIADIAZINE-2,2-DIOXIDES BEARING HETEROCYCLIC LINKERS AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2025-05-29 | — | — | US | disclosed |
| EP-4475845-A1 | A1H-BENZO[C][1,2]THIADIAZINE-2,2-DIOXIDES BEARING HETEROCYCLIC LINKERS AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS | Georgetown University (US) | 2024-12-18 | — | — | EP | disclosed |
| CN-118973573-A | 1H-benzo [ c ] [1,2] thiadiazine-2, 2-dioxides carrying a heterocyclic linker as selective histone deacetylase 6 inhibitors | 乔治城大学 | 2024-11-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171433-A1 | A1H-BENZO[C][1,2]THIADIAZINE-2,2-DIOXIDES BEARING HETEROCYCLIC LINKERS AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS | HDAC1, HDAC6, HDAC11 | HDAC6 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.