Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | TTK | P33981 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 12/20 | 0.44 |
| ▸ | LOXL3 | P58215 | 4/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.44 |
| ▸ | LOX | P28300 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.42 |
| ▸ | CDK1 | P06493 | 4/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.42 |
| ▸ | CDK2 | P24941 | 4/20 | 0.42 |
| ▸ | CDK9 | P50750 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31259731 | 0.88 | LOXL2 (0.55) | CCNCCDK8TTKAURKAAURKB | |
| SCHEMBL31259676 | 0.84 | LOXL2 (0.42) | CCNCCDK8TTKAURKAAURKB | |
| SCHEMBL31259710 | 0.84 | AURKA (0.43) | TTKAURKAAURKBINCENPLOXL2 | |
| SCHEMBL31259643 | 0.79 | CCNC (0.47) | CCNCCDK8LOXL2LOXL3AOC3 | |
| SCHEMBL29764345 | 0.78 | CCNC (0.64) | CCNCCDK8CCNT1CCNB2CCNE2 | |
| SCHEMBL1571332 | 0.74 | ERN1 (0.46) | TTKAURKAAURKBINCENPLOXL2 | |
| SCHEMBL626824 | 0.73 | CCNC (0.43) | CCNCCDK8CCNT1CCNB2CCNE2 | |
| SCHEMBL24582852 | 0.72 | AURKA (0.43) | TTKAURKAAURKBINCENPLOXL2 | |
| SCHEMBL17680442 | 0.72 | ERN1 (0.49) | TTKAURKAAURKBINCENPCCNT1 | |
| SCHEMBL19576888 | 0.72 | AXL (0.44) | CCNCCDK8TTKAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024254527-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | INTERLINE THERAPEUTICS, INC. (US) | 2024-12-12 | — | — | WO | disclosed |