Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 15/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 14/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14789985 | 1.00 | CYP11B2 (0.58) | CYP11B2CYP11B1KMT2ATDP1 | |
| SCHEMBL14789984 | 0.94 | CYP11B2 (0.59) | CYP11B2CYP11B1KMT2ATDP1 | |
| SCHEMBL31260048 | 0.94 | CYP11B2 (0.59) | CYP11B2CYP11B1KMT2ATDP1 | |
| SCHEMBL22005312 | 0.84 | CYP11B1 (0.58) | CYP11B2CYP11B1 | |
| SCHEMBL14789950 | 0.81 | CYP11B2 (0.55) | CYP11B2CYP11B1 | |
| SCHEMBL31259952 | 0.81 | CYP11B2 (0.55) | CYP11B2CYP11B1 | |
| SCHEMBL31259947 | 0.81 | CYP11B2 (0.55) | CYP11B2CYP11B1 | |
| SCHEMBL31259961 | 0.81 | CYP11B2 (0.55) | CYP11B2CYP11B1 | |
| SCHEMBL14789951 | 0.81 | CYP11B2 (0.55) | CYP11B2CYP11B1 | |
| SCHEMBL14780425 | 0.80 | CYP11B2 (0.64) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653618-B1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2025-01-08 | — | — | EP | disclosed |