Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cholecalciferol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR known ✓ | P11473 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | HSPD1 | P10809 | 2/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 2/20 | 1.00 |
| ▸ | HSPE1 | P61604 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | CDC25A | P30304 | 1/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 1/20 | 1.00 |
| ▸ | GLRA1 | P23415 | 1/20 | 1.00 |
| ▸ | DRD3 | P35462 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cholecalciferol SCHEMBL8082779 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| Cholecalciferol SCHEMBL13475366 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| Cholecalciferol SCHEMBL4545272 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| Cholecalciferol SCHEMBL2734123 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| Cholecalciferol SCHEMBL13717177 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| Cholecalciferol SCHEMBL4873580 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| Cholecalciferol SCHEMBL23878716 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| Cholecalciferol SCHEMBL13989117 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| Cholecalciferol SCHEMBL21264875 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| Cholecalciferol SCHEMBL20511118 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 77687 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144835-A1 | MULTIFUNCTIONAL NUTRACEUTICAL FOR ENHANCING FEMALE HEALTH | Beltran, Robert R. (US) | 2026-05-28 | — | — | US | claimed |
| US-20260144836-A1 | NUTRACEUTICAL FOR ENHANCED COGNITIVE PERFORMANCE | Herbanized Wellness, LLC (US) | 2026-05-28 | — | — | US | claimed |
| US-12636281-B2 | Dietary supplements to ameliorate dietary inadequacies related to brain health or neurodegenerative diseases, and methods to design dietary supplements | NEURORESERVE INC. (US) | 2026-05-26 | — | — | US | claimed |
| US-12636251-B1 | Glycoside-containing aqueous formulations having a lipophilic active component | Doane Technology Group LLC (US) | 2026-05-26 | — | — | US | claimed |
| CN-119280171-B | High-stability vitamin D3 particles and preparation method thereof | CHINA RESOURCES SANJIU MEDICAL & PHARMACEUTICAL CO.,LTD. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122081419-A | Method for efficiently converting 7-dehydrocholesterol into vitamin D3 | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075555-A | Visual caries-preventing probiotic lozenge and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122074633-A | Flavour composition, aqueous food composition containing said flavour composition, preparation and use thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122074602-A | High-protein biological fermentation type aquatic feed and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-119949528-B | Composition with effect of improving bone mineral density and preparation method, application and product thereof | GUANGDONG JUNJOY NUTRITIONAL MEDICINE Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| WO-1984002845-A1 | VITAMIN-CONTAINING SKIN CARE OINTMENT | ADVANCED DRUG TECH (US) | 1984-08-02 | — | — | WO | claimed |
| WO-1984001577-A1 | A PROCESS FOR PREPARING A CYCLOADDITION COMPOUND | WYNBERG HANS | 1984-04-26 | — | — | WO | claimed |
| EP-0092004-A1 | Novel vitamin D3 derivatives, processes for preparation thereof, and antigens comprising said derivatives to be used for preparation of antibodies for immunochemical assay and antibodies prepared therefrom | TEIJIN LIMITED (JP) | 1983-10-26 | — | — | EP | claimed |
| EP-0081793-A1 | Novel vitamin D3 derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1983-06-22 | — | — | EP | claimed |
| EP-0078704-A1 | Intermediates in the synthesis of vitamin D derivatives | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1983-05-11 | — | — | EP | claimed |
| EP-0077353-A1 | 1-HYDROXYLATION PROCESS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1983-04-27 | — | — | EP | claimed |
| WO-1982003864-A1 | 1-HYDROXYLATION PROCESS | WISCONSIN ALUMNI RES FOUND (US) | 1982-11-11 | — | — | WO | claimed |
| US-4341774-A | Method for suppressing abnormal rise in immunological function and agent useful therefor | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-07-27 | — | — | US | claimed |
| EP-0028484-A1 | Process for the preparation of active-type vitamin D3 compounds and of the cholesta-5,7-diene precursors, and products so obtained | TEIJIN LIMITED (JP) | 1981-05-13 | — | — | EP | claimed |
| EP-0019000-A1 | OSTEOPLASTIC PROMOTOR | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | claimed |