Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | PRKDC | P78527 | 9/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3121805 | 0.86 | PRKDC (0.48) | IKBKBPRKDCPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3119596 | 0.86 | PIK3CD (0.56) | IKBKBPRKDCPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3235183 | 0.78 | RIPK2 (0.46) | PRKDCALDH1A1KDM4EGAAMAPT | |
| SCHEMBL10298276 | 0.75 | PRKDC (0.49) | PRKDCALDH1A1KDM4EGAAMAPT | |
| Hydrochloric Acid SCHEMBL5010640 | 0.72 | PIK3CD (0.74) | IKBKBPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL10298247 | 0.72 | PIK3CD (0.50) | PRKDCPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL2770127 | 0.70 | MAPT (0.49) | IKBKBPRKDCALDH1A1KDM4EGAA | |
| SCHEMBL28725597 | 0.70 | MAPT (0.55) | PRKDCALDH1A1KDM4EGAAMAPT | |
| SCHEMBL31078702 | 0.70 | ATM (0.46) | IKBKBPIK3CAPIK3CDPIK3CBALDH1A1 | |
| SCHEMBL28725552 | 0.70 | IKBKB (0.43) | IKBKBPRKDCPIK3CAPIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001126-A1 | THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-01-07 | — | — | WO | disclosed |