Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3119596 | 0.79 | PIK3CD (0.56) | ALDH1A1SMN1; SMN2RAB9AKDM4EGAA | |
| SCHEMBL3121805 | 0.79 | PRKDC (0.48) | ALDH1A1LMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL3126013 | 0.78 | IKBKB (0.52) | ALDH1A1LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL10298276 | 0.69 | PRKDC (0.49) | ALDH1A1HTTTSHRKDM4EGAA | |
| SCHEMBL23815324 | 0.69 | LMNA (0.47) | ALDH1A1LMNASMN1; SMN2MAPK14NPC1 | |
| SCHEMBL27029191 | 0.67 | PRKDC (0.44) | ALDH1A1LMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL13162377 | 0.67 | KDM4E (0.60) | ALDH1A1SMN1; SMN2MAPK14NPC1CNR2 | |
| SCHEMBL14507570 | 0.67 | CHRM4 (0.46) | ALDH1A1LMNANPC1RAB9AKDM4E | |
| SCHEMBL10298247 | 0.66 | PIK3CD (0.50) | ALDH1A1SMN1; SMN2RAB9AKDM4EGAA | |
| SCHEMBL13162015 | 0.66 | NPC1 (0.55) | ALDH1A1SMN1; SMN2NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001126-A1 | THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-01-07 | — | — | WO | disclosed |