⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15857711 | 0.72 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL11557297 | 0.70 | LMNA (0.43) | — | |
| SCHEMBL11583128 | 0.70 | LMNA (0.43) | — | |
| SCHEMBL11551651 | 0.70 | LMNA (0.43) | — | |
| SCHEMBL428490 | 0.70 | — | — | |
| SCHEMBL11555740 | 0.70 | LMNA (0.43) | — | |
| SCHEMBL11865606 | 0.70 | LMNA (0.43) | — | |
| SCHEMBL13186521 | 0.70 | — | — | |
| SCHEMBL22479793 | 0.70 | — | — | |
| SCHEMBL1805763 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590707-B | Polyethylene oxide containing N-acetylmorpholinyl functional group and preparation method thereof | 大连理工大学 | 2022-04-12 | — | — | CN | claimed |
| CN-110590707-A | Polyethylene oxide containing N-acetylmorpholinyl functional group and preparation method thereof | 大连理工大学 | 2019-12-20 | — | — | CN | claimed |
| CN-110590707-B | Polyethylene oxide containing N-acetylmorpholinyl functional group and preparation method thereof | 大连理工大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-110590707-A | Polyethylene oxide containing N-acetylmorpholinyl functional group and preparation method thereof | 大连理工大学 | 2019-12-20 | — | — | CN | disclosed |
| EP-1491537-B1 | HYDROXYMORPHOLINONE DERIVATIVE AND MEDICINAL USE THEREOF | SENJU PHARMA CO (JP) | 2010-07-07 | — | — | EP | disclosed |
| CN-100422161-C | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMA CO (JP) | 2008-10-01 | — | — | CN | disclosed |
| US-7223755-B2 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| US-7223755-B2 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2007-05-29 | — | — | US | disclosed |
| CN-1656084-A | Hydroxymorpholone derivative and medical application thereof | SENJU PHARMA CO (JP) | 2005-08-17 | — | — | CN | disclosed |
| US-20050176704-A1 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
| US-20050176704-A1 | Hydroxymorpholinone derivative and medicinal use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |