Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13197433 | 1.00 | HTR2C (0.61) | HTR2CESR2LIPEDRD2DRD4 | |
| SCHEMBL13197432 | 1.00 | HTR2C (0.61) | HTR2CESR2LIPEDRD2DRD4 | |
| SCHEMBL11280521 | 0.94 | HTR2C (0.56) | HTR2CESR2 | |
| SCHEMBL4434726 | 0.94 | HTR2C (0.56) | HTR2CESR2LIPEDRD2DRD4 | |
| SCHEMBL26480380 | 0.94 | HTR2C (0.56) | HTR2CESR2 | |
| SCHEMBL1847401 | 0.89 | HTR2C (0.73) | HTR2CKDM1A | |
| SCHEMBL17147616 | 0.89 | HTR2C (0.53) | HTR2CESR2KDM1ARCOR1 | |
| SCHEMBL19102561 | 0.89 | HTR2C (0.53) | HTR2CESR2KDM1ARCOR1 | |
| SCHEMBL17147613 | 0.89 | HTR2C (0.53) | HTR2CESR2KDM1ARCOR1 | |
| SCHEMBL9220519 | 0.88 | HTR2C (0.50) | HTR2CESR2LIPEKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| WO-2012025182-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |