Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.73 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanide SCHEMBL27770959 | 0.93 | HTR2C (0.66) | HTR2CMAOBKDM1A | |
| Dimethylamine SCHEMBL27903575 | 0.91 | HTR2C (0.63) | HTR2CMAOBKDM1A | |
| SCHEMBL5147805 | 0.91 | HTR2C (0.68) | HTR2CKDM1A | |
| SCHEMBL2539686 | 0.91 | HTR2C (0.68) | HTR2CKDM1A | |
| SCHEMBL23484594 | 0.89 | HTR2C (0.61) | HTR2C | |
| SCHEMBL8597879 | 0.89 | HTR2C (0.61) | HTR2CMAOBKDM1A | |
| SCHEMBL8597881 | 0.89 | HTR2C (0.61) | HTR2CMAOBKDM1AMAOA | |
| SCHEMBL13197432 | 0.89 | HTR2C (0.61) | HTR2CKDM1A | |
| SCHEMBL8597880 | 0.89 | HTR2C (0.61) | HTR2CMAOBKDM1A | |
| SCHEMBL31263 | 0.89 | HTR2C (0.61) | HTR2CKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812133-B | Alpha, alpha-difluoroallyl organometallic compound and preparation method and application thereof | 南京工业大学 | 2022-03-11 | — | — | CN | claimed |
| CN-112812133-A | Alpha, alpha-difluoroallyl organometallic compound and preparation method and application thereof | 南京工业大学 | 2021-05-18 | — | — | CN | claimed |
| US-20070287699-A1 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-12-13 | — | — | US | claimed |
| WO-2007130499-A2 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-11-15 | — | — | WO | claimed |
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U S INC (US) | 2026-01-08 | — | — | US | disclosed |
| CN-112812133-B | Alpha, alpha-difluoroallyl organometallic compound and preparation method and application thereof | 南京工业大学 | 2022-03-11 | — | — | CN | disclosed |
| US-11021427-B2 | Pd(II)-catalyzed enantioselective C—H arylation of free carboxylic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-06-01 | — | — | US | disclosed |
| CN-112812133-A | Alpha, alpha-difluoroallyl organometallic compound and preparation method and application thereof | 南京工业大学 | 2021-05-18 | — | — | CN | disclosed |
| WO-2021078995-A1 | SELECTIVE POLYPEPTIDE SYNTHESIS STALLING ASSAY AND COMPOUND | UMC UTRECHT HOLDING B.V. (NL) | 2021-04-29 | — | — | WO | disclosed |
| EP-3811945-A1 | COMPOUNDS FOR TREATING AND PREVENTING GROWTH HORMONE RECEPTOR-DEPENDENT CONDITIONS | UMC Utrecht Holding B.V. (NL) | 2021-04-28 | — | — | EP | disclosed |
| US-10821100-B2 | Triazolone compounds as mPGES-1 inhibitors | Ichnos Sciences SA (CH) | 2020-11-03 | — | — | US | disclosed |
| WO-2019204477-A1 | PD(II)-CATALYZED ENANTIOSELECTIVE C-H ARYLATION OF FREE CARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-10-24 | — | — | WO | disclosed |
| WO-2010010154-A1 | 3,4-DIARYLPYRAZOLES AS PROTEIN KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2010-01-28 | — | — | WO | disclosed |
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070287699-A1 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-12-13 | — | — | US | disclosed |
| US-20070287699-A1 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-12-13 | — | — | US | disclosed |
| WO-2007130499-A2 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-11-15 | — | — | WO | disclosed |
| US-20070259936-A1 | Benzimidazole Modulators of VR1 | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-08 | — | — | US | disclosed |
| CN-101012184-A | Fluorine-containing cyclopropane and synthetic method thereof | UNIV SHANGHAI (CN) | 2007-08-08 | — | — | CN | disclosed |
| EP-0832073-B1 | QUINAZOLINES AND PHARMACEUTICAL COMPOSITIONS | SUGEN INC (US) | 2002-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | KCNA5, KCNH1, KCNK5 | HTR2C 3081/4885MAOB 2969/4885KDM1A 196/4885 |
| US-20070259936-A1 | Benzimidazole Modulators of VR1 | VRK1, VRK2, VIL1 | HTR2C 371/4885MAOB 2944/4885KDM1A 1102/4885 |
| US-20070287699-A1 | ANTIVIRAL AGENTS | EIF2AK2, MAVS, ZC3HAV1 | HTR2C 4453/4885MAOB 3428/4885KDM1A 4133/4885 |
| US-11021427-B2 | Pd(II)-catalyzed enantioselective C—H arylation of free carboxylic acids | PDCD1, PDK3, PDCD1LG2 | HTR2C 770/4885MAOB 222/4885KDM1A 1577/4885 |
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | NOD1, NLRP3, NOD2 | HTR2C 1515/4885MAOB 2926/4885KDM1A 4256/4885 |
| US-10821100-B2 | Triazolone compounds as mPGES-1 inhibitors | PTGES, PTGS1, PTGIS | HTR2C 653/4885MAOB 300/4885KDM1A 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.