SCHEMBL31263113

SCHEMBL31263113

CC12C=C(B3OC(C)(C)C(C)(C)O3)CC(C)(CC1)O2

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ P2RX7 Q99572 1/20 0.40
▸ MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18095998 0.71 P2RX7 (0.48) P2RX7MAPK1
SCHEMBL3655929 0.69 P2RX7 (0.47) P2RX7MAPK1
SCHEMBL3652609 0.68 P2RX7 (0.42) P2RX7MAPK1
SCHEMBL25136361 0.67 MAPK1 (0.46) P2RX7MAPK1
SCHEMBL30708588 0.66 P2RX7 (0.43) P2RX7MAPK1
SCHEMBL2753979 0.66 P2RX7 (0.43) P2RX7MAPK1
SCHEMBL21585195 0.66 P2RX7 (0.40) P2RX7MAPK1
SCHEMBL24514841 0.64 P2RX7 (0.50) P2RX7MAPK1
SCHEMBL12498446 0.64 P2RX7 (0.42) P2RX7MAPK1
SCHEMBL17611948 0.64 P2RX7 (0.35) P2RX7MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709719-A1 5-CYANO-1H-IMIDAZOLE-2-CARBOXAMIDE COMPOUNDS AS CSF1R INHIBITORS Modulo Bio, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024254440-A1 5-CYANO-1H-IMIDAZOLE-2-CARBOXAMIDE COMPOUNDS AS CSF1R INHIBITORS MODULO BIO, INC. (US) 2024-12-12 — — WO disclosed
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