SCHEMBL312632

SCHEMBL312632

CC(=CC(F)C(F)(F)C(F)C(F)F)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1482323 0.84 PTGS1 (0.32) PTGS1
SCHEMBL2326834 0.83
SCHEMBL1171214 0.80
SCHEMBL403113 0.79 PTGS1 (0.30) PTGS1
SCHEMBL5925117 0.79
SCHEMBL5704479 0.79
SCHEMBL29193725 0.78
SCHEMBL2829521 0.76
SCHEMBL1703519 0.74
SCHEMBL2784307 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1714195-A2 ORMOSIL AEROGELS CONTAINING SILICON BONDED POLYMETHACRYLATE Aspen Aerogels Inc. (US) 2006-10-25 EP claimed
WO-2005098553-A2 ORMOSIL AEROGELS CONTAINING SILICON BONDED POLYMETHACRYLATE ASPEN AEROGELS, INC. (US) 2005-10-20 WO claimed
US-20050192366-A1 Ormosil aerogels containing silicon bonded polymethacrylate ASPEN AEROGELS, INC. (US) 2005-09-01 US claimed
US-6228562-B1 FORMING PHOTORESIST PATTERN; EXPOSURE TO LIGHT NEC CORPORATION (JP) 2001-05-08 US claimed
EP-0706399-A4 COMPOSITIONS AND PROCESS FOR REMOVING BILE SALTS GELTEX PHARMA INC (US) 1998-08-12 EP claimed
US-5703188-A Process for removing bile salts from a patient and compositions therefor GELTEX PHARMACEUTICALS, INC. (US) 1997-12-30 US claimed
US-5624963-A Process for removing bile salts from a patient and compositions therefor GELTEX PHARMACEUTICALS, INC. (US) 1997-04-29 US claimed
EP-0764177-A1 CROSS-LINKED POLYMERS FOR REMOVING BILE SALTS FROM A PATIENT GELTEX PHARMACEUTICALS, INC. (US) 1997-03-26 EP claimed
EP-0706399-A1 COMPOSITIONS AND PROCESS FOR REMOVING BILE SALTS GELTEX PHARMACEUTICALS, INC. (US) 1996-04-17 EP claimed
WO-1995034588-A1 CROSS-LINKED POLYMERS FOR REMOVING BILE SALTS FROM A PATIENT GELTEX PHARMACEUTICALS, INC. (US) 1995-12-21 WO claimed
WO-1994027620-A1 COMPOSITIONS AND PROCESS FOR REMOVING BILE SALTS GELTEX PHARMACEUTICALS, INC. (US) 1994-12-08 WO claimed
EP-0216074-B1 POLYVINYL ALCOHOL DERIVATIVES AND CROSSLINKED HYDROGEL CONTACT LENSES MADE THEREFROM CIBA-GEIGY AG (CH) 1993-06-16 EP claimed
US-5084537-A Contact lenses from organosilicon monomers that are oxygen permeable BAUSCH & LOMB, INCORPORATED (US) 1992-01-28 US claimed
US-5002979-A Hyydrogenorganosilicon monomer, organosilicon, fluoroorgano monomer, a hydrophobic monomer and a crosslinking agent BAUSCH & LOMB INCORPORATED (US) 1991-03-26 US claimed
EP-0211067-B1 OXYGEN-PERMEABLE LENSES Bausch & Lomb Incorporated (US) 1991-03-13 EP claimed
EP-0216074-A2 Polyvinyl alcohol derivatives and crosslinked hydrogel contact lenses made therefrom CIBA-GEIGY AG (CH) 1987-04-01 EP claimed
EP-0211067-A1 OXYGEN-PERMEABLE LENSES. BAUSCH & LOMB (US) 1987-02-25 EP claimed
EP-0209597-A1 EXTENDED-WEAR LENSES Bausch & Lomb Incorporated (US) 1987-01-28 EP claimed
WO-1986004342-A1 OXYGEN-PERMEABLE LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO claimed
WO-1986004343-A1 EXTENDED-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO claimed