Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.55 |
| ▸ | GSPT1 | P15170 | 3/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | WIZ | O95785 | 1/20 | 0.48 |
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31264436 | 0.87 | CRBN (0.58) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL31264408 | 0.87 | CRBN (0.69) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL31264435 | 0.87 | CRBN (0.60) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL63298 | 0.87 | CRBN (0.59) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL31264443 | 0.86 | CRBN (0.56) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL31264450 | 0.85 | CRBN (0.73) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL31264424 | 0.85 | CRBN (0.66) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL31264439 | 0.85 | CRBN (0.55) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL31264440 | 0.83 | CRBN (0.59) | CRBNGSPT1DDB1IKZF3CYP2C19 | |
| SCHEMBL13578932 | 0.82 | CRBN (0.62) | CRBNGSPT1DDB1IKZF3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024251301-A1 | GSPT1 PROTEIN DEGRADER CONTAINING OXIME STRUCTURE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2024-12-12 | — | — | WO | disclosed |
| CN-119080738-A | GSPT1 protein degradation agent containing oxime structure and preparation method and application thereof | 中国药科大学 | 2024-12-06 | — | — | CN | disclosed |