Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.51 |
| ▸ | FEN1 | P39748 | 3/20 | 0.51 |
| ▸ | EIF2AK3 | Q9NZJ5 | 15/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.41 |
| ▸ | EIF2AK1 | Q9BQI3 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | YES1 | P07947 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26106772 | 0.88 | CYP3A4 (0.56) | ALOX5APFEN1EIF2AK3RIPK1CYP3A4 | |
| SCHEMBL29407664 | 0.88 | CYP3A4 (0.56) | ALOX5APFEN1EIF2AK3RIPK1CYP3A4 | |
| SCHEMBL31264724 | 0.85 | CYP3A4 (0.45) | EIF2AK3CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31264720 | 0.83 | CYP3A4 (0.51) | ALOX5APFEN1EIF2AK3RIPK1CYP3A4 | |
| SCHEMBL31264744 | 0.77 | EIF2AK3 (0.47) | EIF2AK3RIPK1EIF2AK2EIF2AK1 | |
| SCHEMBL31264751 | 0.77 | CYP3A4 (0.45) | ALOX5APFEN1EIF2AK3RIPK1CYP3A4 | |
| SCHEMBL31264730 | 0.76 | CYP3A4 (0.46) | ALOX5APFEN1EIF2AK3RIPK1CYP3A4 | |
| SCHEMBL25640015 | 0.76 | CYP3A4 (0.46) | ALOX5APFEN1EIF2AK3RIPK1CYP3A4 | |
| SCHEMBL31264736 | 0.75 | EIF2AK3 (0.44) | EIF2AK3RIPK1EIF2AK2EIF2AK1LCK | |
| SCHEMBL31264749 | 0.75 | EIF2AK3 (0.47) | EIF2AK3RIPK1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894900-A | Pyrrolo pyrimidine derivative and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024251147-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 康百达（四川）生物医药科技有限公司 | 2024-12-12 | — | — | WO | disclosed |