Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 16/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.42 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31264744 | 0.85 | EIF2AK3 (0.47) | EIF2AK3EIF2AK2EIF2AK1RIPK1 | |
| SCHEMBL31264694 | 0.81 | CYP2C9 (0.42) | LCKSRCKDRTEKRIPK2 | |
| SCHEMBL29407664 | 0.77 | CYP3A4 (0.56) | EIF2AK3METAXLRIPK1 | |
| SCHEMBL26106772 | 0.77 | CYP3A4 (0.56) | EIF2AK3METAXLRIPK1 | |
| SCHEMBL31264749 | 0.77 | EIF2AK3 (0.47) | EIF2AK3METAXLRIPK1 | |
| SCHEMBL20351783 | 0.77 | RIPK2 (0.61) | EIF2AK3SRCRIPK2METAXL | |
| SCHEMBL13020096 | 0.76 | SRC (0.69) | EIF2AK3LCKSRCKDRTEK | |
| SCHEMBL31264693 | 0.75 | ALOX5AP (0.51) | EIF2AK3LCKEIF2AK2EIF2AK1AXL | |
| SCHEMBL31264724 | 0.75 | CYP3A4 (0.45) | EIF2AK3RIPK2METAXL | |
| SCHEMBL23917445 | 0.74 | PIK3CD (0.57) | EIF2AK3SRCKDRMETAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722216-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| CN-119894900-A | Pyrrolo pyrimidine derivative and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024251147-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 康百达（四川）生物医药科技有限公司 | 2024-12-12 | — | — | WO | disclosed |