SCHEMBL312647

SCHEMBL312647

Cc1cc(Nc2ccc(N(C)C)cc2)cc(F)c1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 7/20 0.41
▸ SOS1 Q07889 1/20 0.41
▸ JAK2 O60674 1/20 0.38
▸ JAK1 P23458 1/20 0.38
▸ TYK2 P29597 1/20 0.38
▸ JAK3 P52333 1/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ CYP3A4 P08684 3/20 0.38
▸ ALOX15 P16050 3/20 0.38
▸ TDP1 Q9NUW8 2/20 0.38
▸ THRB P10828 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ TP53 P04637 2/20 0.38
▸ MAPK1 P28482 2/20 0.38
▸ USP2 O75604 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ GLA P06280 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8778006 0.86 KDM1A (0.40) KDM1AJAK2JAK1TYK2JAK3
SCHEMBL536827 0.83 NPC1 (0.42) KDM1ASOS1JAK2JAK1TYK2
SCHEMBL312328 0.81 MAPT (0.44) KDM1AJAK2JAK1TYK2JAK3
SCHEMBL313137 0.79 KDM1A (0.36) KDM1AJAK2JAK1TYK2JAK3
SCHEMBL8778029 0.77 ALDH3A1 (0.48) JAK2JAK1TYK2JAK3ALDH1A1
SCHEMBL28480236 0.76 MAPT (0.44) ALDH1A1CYP3A4ALOX15TDP1KMT2A
SCHEMBL11330095 0.75 GAA (0.67) KDM1AALDH1A1CYP3A4ALOX15TDP1
SCHEMBL312377 0.74 KDM1A (0.41) KDM1AJAK2JAK1TYK2JAK3
SCHEMBL8003398 0.74 KDM1A (0.43) KDM1AJAK2JAK1TYK2JAK3
SCHEMBL7753253 0.74 NPC1 (0.40) KDM1AJAK2JAK1TYK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030139293-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2003-07-24 — — US claimed
EP-0325231-B1 Heat-sensitive recording material JUJO PAPER CO LTD (JP) 1994-06-22 — — EP claimed
EP-0287121-B1 HEAT AND LIGHT-SENSITIVE RECORDING MATERIAL AND RECORDING METHOD JUJO PAPER CO., LTD. (JP) 1993-08-04 — — EP claimed
EP-0286116-B1 HEAT-SENSITIVE RECORDING MATERIAL JUJO PAPER CO., LTD. (JP) 1991-12-11 — — EP claimed
US-4971942-A Colorless basic chromogenic cye, divinyl compound, fluorane-type leuco dye JUJO PAPER CO., LTD. (JP) 1990-11-20 — — US claimed
US-4853363-A Heat-sensitive recording material JUJO PAPER CO., LTD. (JP) 1989-08-01 — — US claimed
US-4853361-A FLUORAN-TYPE LEUCO DYES JUJO PAPER CO., LTD. (JP) 1989-08-01 — — US claimed
US-4853362-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1989-08-01 — — US claimed
EP-0325231-A2 Heat-sensitive recording material NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1989-07-26 — — EP claimed
EP-0286116-A2 Heat-sensitive recording material JUJO PAPER CO., LTD. (JP) 1988-10-12 — — EP claimed
US-20240001654-A1 Multilayer Body, Card, Passport, Method for Producing Multilayer Body, Method for Producing Card, Method for Producing Passport, and Laser Marking Method MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-04 — — US disclosed
EP-4297978-A1 COMPOSITIONS AND METHODS FOR SENSITIZING HEAT MEDIA Solenis Technologies Cayman, L.P. (CH) 2024-01-03 — — EP disclosed
EP-4296055-A1 MULTILAYER BODY, CARD, PASSPORT, METHOD FOR PRODUCING MULTILAYER BODY, METHOD FOR PRODUCING CARD, METHOD FOR PRODUCING PASSPORT, AND LASER MARKING METHOD Mitsubishi Chemical Corporation (JP) 2023-12-27 — — EP disclosed
WO-2023190314-A1 HEAT-SENSITIVE RECORDING BODY 日本製紙株式会社 2023-10-05 — — WO disclosed
WO-2023190315-A1 HEAT-SENSITIVE RECORDING BODY 日本製紙株式会社 2023-10-05 — — WO disclosed
US-4853363-A Heat-sensitive recording material JUJO PAPER CO., LTD. (JP) 1989-08-01 — — US disclosed
EP-0325231-A2 Heat-sensitive recording material NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1989-07-26 — — EP disclosed
EP-0307836-A2 Heat-sensitive recording material JUJO PAPER CO., LTD. (JP) 1989-03-22 — — EP disclosed
EP-0287121-A2 Heat and light-sensitive recording material and recording method JUJO PAPER CO., LTD. (JP) 1988-10-19 — — EP disclosed
EP-0286116-A2 Heat-sensitive recording material JUJO PAPER CO., LTD. (JP) 1988-10-12 — — EP disclosed
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