Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 18/20 | 0.80 |
| ▸ | TPSB2 | P20231 | 6/20 | 0.61 |
| ▸ | F11 | P03951 | 6/20 | 0.61 |
| ▸ | PLAU | P00749 | 2/20 | 0.61 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.61 |
| ▸ | PLG | P00747 | 1/20 | 0.61 |
| ▸ | F7 | P08709 | 1/20 | 0.61 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21438222 | 1.00 | CFD (0.80) | CFDTPSB2F11PLAUKLKB1 | |
| SCHEMBL21439066 | 0.89 | CFD (1.00) | CFDTPSB2F11PLAUKLKB1 | |
| SCHEMBL21438913 | 0.84 | CFD (0.61) | CFDTPSB2F11PLAUKLKB1 | |
| SCHEMBL23607742 | 0.82 | CFD (0.67) | CFDTPSB2F11PLAUKLKB1 | |
| SCHEMBL16397008 | 0.77 | CFD (1.00) | CFDTPSB2F11PLAUKLKB1 | |
| SCHEMBL31266556 | 0.77 | CFD (0.74) | CFDTPSB2F11PLAUKLKB1 | |
| SCHEMBL21439660 | 0.77 | CFD (0.74) | CFDTPSB2F11PLAUKLKB1 | |
| SCHEMBL23218685 | 0.76 | CFD (0.65) | CFDTPSB2F11PLAUKLKB1 | |
| SCHEMBL23218404 | 0.76 | CFD (0.65) | CFDTPSB2F11PLAUKLKB1 | |
| SCHEMBL29592669 | 0.76 | CFD (0.65) | CFDTPSB2F11PLAUKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-B1 | SUBSTITUTED BENZOPYRROLE AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2024-10-02 | — | — | EP | disclosed |