Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | DHODH | Q02127 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31266761 | 0.86 | MEN1 (0.61) | MEN1KMT2ADHODHKDM4EALDH1A1 | |
| SCHEMBL14518623 | 0.83 | MEN1 (0.72) | MEN1KMT2ADHODHKDM4EALDH1A1 | |
| SCHEMBL1900020 | 0.81 | MEN1 (0.70) | MEN1KMT2ADHODHKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4562712 | 0.80 | MEN1 (0.69) | MEN1KMT2ADHODHKDM4EALDH1A1 | |
| Bromide SCHEMBL4383984 | 0.80 | MEN1 (0.69) | MEN1KMT2ADHODHKDM4EALDH1A1 | |
| SCHEMBL31266687 | 0.79 | KLK7 (0.61) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL31266736 | 0.79 | MEN1 (0.46) | MEN1KMT2ADHODHKDM4EALDH1A1 | |
| SCHEMBL2576382 | 0.79 | KDM4E (0.76) | MEN1KMT2ADHODHKDM4EALDH1A1 | |
| SCHEMBL28693348 | 0.79 | KDM4E (0.72) | MEN1KMT2ADHODHKDM4EALDH1A1 | |
| SCHEMBL14518625 | 0.78 | MEN1 (0.66) | MEN1KMT2ADHODHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724430-A1 | CONDENSED AZINES AS INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE | Flagship Pioneering Innovations VI, LLC (US) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024254396-A1 | CONDENSED AZINES AS INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE | FLAGSHIP PIONEERING INNOVATIONS, VI, LLC (US) | 2024-12-12 | — | — | WO | disclosed |