Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.67 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.67 |
| ▸ | DHODH | Q02127 | 1/20 | 0.67 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4562712 | 0.97 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14518623 | 0.97 | MEN1 (0.72) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14518625 | 0.91 | MEN1 (0.66) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2576382 | 0.89 | KDM4E (0.76) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL28090814 | 0.84 | MEN1 (0.72) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL19508618 | 0.84 | MEN1 (0.70) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16307495 | 0.84 | MAPT (0.74) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL19508777 | 0.84 | TACR3 (0.65) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL4208879 | 0.83 | PLA2G2A (0.79) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL17923184 | 0.83 | MAPT (0.74) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629431-B2 | Polycarbonate prepolymer for solid phase polymerization and process for producing polycarbonate | IDEMITSU KOSAN CO., LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20080064847-A1 | Oxidative carbonylation; molecular weight control | IDEMISU KOSAN CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |