Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 9/20 | 0.76 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | STAT3 | P40763 | 1/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.60 |
| ▸ | INSR | P06213 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3136515 | 1.00 | MAP3K5 (0.76) | MAP3K5TNFRSF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL3136503 | 1.00 | MAP3K5 (0.76) | MAP3K5TNFRSF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL3900346 | 0.93 | MAP3K5 (0.78) | MAP3K5TNFRSF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL3900350 | 0.93 | MAP3K5 (0.78) | MAP3K5TNFRSF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL13821857 | 0.92 | TNFRSF1A (0.67) | MAP3K5TNFRSF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL13813621 | 0.91 | TNFRSF1A (0.66) | MAP3K5TNFRSF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL3897831 | 0.88 | MAP3K5 (0.78) | MAP3K5TNFRSF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL3897828 | 0.88 | MAP3K5 (0.78) | MAP3K5TNFRSF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL3134456 | 0.88 | TNFRSF1A (0.74) | MAP3K5TNFRSF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL3134440 | 0.88 | TNFRSF1A (0.74) | MAP3K5TNFRSF1AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | claimed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | claimed |
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2010044924-A1 | NOVEL ANTIVIRAL AGENTS FOR ENVELOPED VIRUSES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120219613-A1 | Novel Antiviral Agents for Enveloped Viruses | MAVS, LAMP1, HAVCR2 | MAP3K5 3869/4885TNFRSF1A 2355/4885MEN1 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.