SCHEMBL31268601

SCHEMBL31268601

Nc1ccc(-c2c(F)c(-c3ccc(N)cc3)c(F)c(-c3ccc(N)cc3)c2F)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
CYP3A4 P08684 4/20 0.56
TDP1 Q9NUW8 3/20 0.56
TP53 P04637 2/20 0.56
MEN1 O00255 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
TAAR1 Q96RJ0 3/20 0.46
HSD17B10 Q99714 3/20 0.46
KIF11 P52732 2/20 0.44
APP P05067 2/20 0.42
ACHE P22303 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
CA14 Q9ULX7 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9479437 0.94 ALDH1A1 (0.56) ALDH1A1CYP3A4TDP1TP53MEN1
SCHEMBL1513191 0.92 ALDH1A1 (0.53) ALDH1A1CYP3A4TDP1TP53MEN1
SCHEMBL14613668 0.89 ALDH1A1 (0.58) ALDH1A1CYP3A4TDP1TP53MEN1
SCHEMBL13385818 0.87 ALDH1A1 (0.48) ALDH1A1CYP3A4TDP1TP53MEN1
SCHEMBL13827302 0.83 ALDH1A1 (0.43) ALDH1A1CYP3A4TDP1TP53MEN1
SCHEMBL1664218 0.79 TDP1 (0.46) ALDH1A1CYP3A4TDP1TP53MEN1
SCHEMBL17104940 0.79 TDP1 (0.40) ALDH1A1CYP3A4TDP1TP53MEN1
SCHEMBL13385813 0.76 ALDH1A1 (0.48) ALDH1A1CYP3A4TDP1TP53MEN1
SCHEMBL6020612 0.75 CYP3A4 (0.62) ALDH1A1CYP3A4TDP1TP53MEN1
SCHEMBL9478914 0.74 ALDH1A1 (0.53) ALDH1A1CYP3A4TDP1TP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119119403-A Fluorine-rich two-dimensional covalent organic framework material with ultra-micropores and preparation method and application thereof 浙江工业大学 2024-12-13 CN disclosed