Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984070 | 0.96 | TLR7 (0.34) | TLR7CNR1KCNH2PIK3CDKDM4E | |
| SCHEMBL30984043 | 0.94 | TLR7 (0.37) | TLR7ACHEKCNH2PIK3CDHRH4 | |
| SCHEMBL31269351 | 0.91 | PIK3CD (0.35) | TLR7CNR1KCNH2PIK3CDHRH4 | |
| SCHEMBL30983885 | 0.91 | CNR1 (0.33) | CNR1KCNH2PIK3CDHRH4 | |
| SCHEMBL31269005 | 0.91 | PDE2A (0.35) | CNR1KCNH2PIK3CDHRH4 | |
| SCHEMBL31268841 | 0.90 | CNR1 (0.33) | CNR1KCNH2PIK3CDKDM4E | |
| SCHEMBL31268985 | 0.90 | TLR7 (0.34) | TLR7PIK3CDKDM4EMAOA | |
| SCHEMBL31269450 | 0.90 | TLR7 (0.34) | TLR7KCNH2PIK3CDHRH4MAOA | |
| SCHEMBL31269267 | 0.89 | CNR1 (0.32) | CNR1KCNH2PIK3CDKDM4EHRH4 | |
| SCHEMBL31269220 | 0.89 | TLR7 (0.38) | TLR7PIK3CDKDM4EMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |