SCHEMBL31268784

SCHEMBL31268784

CO[C@H]1CCN(C(=O)COc2ccc(-c3nc4c(OC5(C)CC5)ncnc4n3Cc3cc(C)ccn3)c(Cl)c2)C1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 20/20 0.40
▸ PIK3R1 P27986 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31269207 0.92 PIK3CD (0.38) PIK3CDPIK3R1
SCHEMBL31268883 0.92 PIK3CD (0.38) PIK3CDPIK3R1
SCHEMBL31269417 0.92 PIK3CD (0.39) PIK3CDPIK3R1
SCHEMBL31269355 0.91 PIK3CD (0.38) PIK3CD
SCHEMBL31268831 0.91 PIK3CD (0.38) PIK3CD
SCHEMBL31269383 0.90 PIK3CD (0.43) PIK3CDPIK3R1
SCHEMBL31269257 0.90 PIK3CD (0.36) PIK3CDPIK3R1
SCHEMBL31269092 0.90 RAB9A (0.40) PIK3CD
SCHEMBL31269232 0.90 RAB9A (0.41) PIK3CD
SCHEMBL31268951 0.90 PIK3CD (0.36) PIK3CDPIK3R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
Send feedback