SCHEMBL31268960

SCHEMBL31268960

CC(CCCOc1ccc(-c2nc3c(OC4(C)CC4)ncnc3n2Cc2cccc(Cl)c2)c(Cl)c1)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LTB4R Q15722 2/20 0.34
▸ TLR7 Q9NYK1 1/20 0.34
▸ CNR1 P21554 1/20 0.34
▸ S1PR1 P21453 2/20 0.33
▸ S1PR3 Q99500 1/20 0.33
▸ PIK3CD O00329 2/20 0.33
▸ AVPR1B P47901 2/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ MAOB P27338 1/20 0.32
▸ PTGDR2 Q9Y5Y4 1/20 0.32
▸ S1PR5 Q9H228 1/20 0.32
▸ PLA2G2A P14555 1/20 0.32
▸ SRC P12931 1/20 0.32
▸ HTR1A P08908 1/20 0.32
▸ DRD2 P14416 1/20 0.32
▸ HTR2A P28223 1/20 0.32
▸ HTR7 P34969 1/20 0.32
▸ HTR6 P50406 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30983474 0.97 CNR1 (0.35) LTB4RTLR7CNR1S1PR1S1PR3
SCHEMBL30983500 0.97 CNR1 (0.35) LTB4RTLR7CNR1S1PR1S1PR3
SCHEMBL30983374 0.97 CNR1 (0.35) LTB4RTLR7CNR1S1PR1S1PR3
SCHEMBL31269370 0.91 CNR1 (0.34) TLR7CNR1S1PR1S1PR3PIK3CD
SCHEMBL31268939 0.91 CNR1 (0.35) LTB4RTLR7CNR1S1PR1PIK3CD
SCHEMBL31268941 0.90 CNR1 (0.34) TLR7CNR1PIK3CDAVPR1BKMT2A
SCHEMBL31268940 0.90 CNR1 (0.34) TLR7CNR1PIK3CDAVPR1BKMT2A
SCHEMBL31269183 0.90 PIK3CD (0.34) S1PR1S1PR3PIK3CDKMT2AS1PR5
SCHEMBL30983523 0.90 PLA2G2A (0.38) TLR7CNR1PIK3CDPTGDR2PLA2G2A
SCHEMBL31269372 0.90 CNR1 (0.35) CNR1S1PR1PIK3CDKMT2APTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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