SCHEMBL31268964

SCHEMBL31268964

CC1(Oc2ncnc3c2nc(-c2ccc(CCCCC(=O)O)cc2Cl)n3Cc2ccccc2C#N)CC1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 2/20 0.37
▸ SLC22A12 Q96S37 1/20 0.34
▸ FFAR1 O14842 2/20 0.33
▸ PIK3CD O00329 2/20 0.32
▸ FFAR4 Q5NUL3 2/20 0.32
▸ TP53 P04637 2/20 0.32
▸ DPP4 P27487 6/20 0.32
▸ CYP3A4 P08684 3/20 0.32
▸ GPR119 Q8TDV5 1/20 0.31
▸ PPARD Q03181 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31268774 0.90 CNR1 (0.36) CNR1PIK3CDDPP4CYP3A4GPR119
SCHEMBL31269337 0.88 CNR1 (0.39) CNR1PIK3CDDPP4CYP3A4GPR119
SCHEMBL31269020 0.85 FFAR4 (0.38) CNR1SLC22A12FFAR1PIK3CDFFAR4
SCHEMBL31269235 0.84 CNR1 (0.38) CNR1PIK3CDDPP4CYP3A4GPR119
SCHEMBL31269364 0.83 CNR1 (0.37) CNR1PIK3CDDPP4CYP3A4GPR119
SCHEMBL31269055 0.83 CNR1 (0.36) CNR1PIK3CDDPP4CYP3A4GPR119
SCHEMBL31268800 0.82 CNR1 (0.38) CNR1PIK3CDDPP4CYP3A4GPR119
SCHEMBL31268994 0.82 CNR1 (0.38) CNR1PIK3CDDPP4CYP3A4GPR119
SCHEMBL31268892 0.82 CNR1 (0.37) CNR1PIK3CDDPP4CYP3A4GPR119
SCHEMBL31268744 0.82 CNR1 (0.37) CNR1PIK3CDDPP4CYP3A4GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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