SCHEMBL31268992

SCHEMBL31268992

CC1(Oc2ncnc3c2nc(-c2ccc(OCCOCCC(=O)O)cc2Cl)n3Cc2cccc(Cl)c2)CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 2/20 0.35
▸ PTGDR2 Q9Y5Y4 1/20 0.34
▸ TLR7 Q9NYK1 1/20 0.33
▸ PLA2G2A P14555 5/20 0.33
▸ PIK3CD O00329 2/20 0.33
▸ MAOB P27338 1/20 0.33
▸ S1PR5 Q9H228 2/20 0.32
▸ PPARG P37231 1/20 0.32
▸ PPARD Q03181 1/20 0.32
▸ HTR6 P50406 1/20 0.32
▸ FFAR1 O14842 1/20 0.31
▸ FFAR4 Q5NUL3 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ USP2 O75604 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ ALOX15 P16050 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31269376 0.97 PPARG (0.34) CNR1PTGDR2TLR7PLA2G2APIK3CD
SCHEMBL31269035 0.96 CNR1 (0.36) CNR1PTGDR2TLR7PLA2G2APIK3CD
SCHEMBL31268778 0.94 PPARG (0.35) CNR1PTGDR2TLR7PLA2G2APIK3CD
SCHEMBL30983422 0.94 PPARG (0.35) CNR1PTGDR2TLR7PLA2G2APIK3CD
SCHEMBL30983523 0.94 PLA2G2A (0.38) CNR1PTGDR2TLR7PLA2G2APIK3CD
SCHEMBL30983451 0.93 PLA2G2A (0.38) CNR1PTGDR2TLR7PLA2G2APIK3CD
SCHEMBL31269373 0.92 PLA2G2A (0.37) CNR1PTGDR2TLR7PLA2G2APIK3CD
SCHEMBL31268872 0.92 PLA2G2A (0.37) CNR1PTGDR2TLR7PLA2G2APIK3CD
SCHEMBL31321937 0.91 PLA2G2A (0.40) PLA2G2APIK3CD
SCHEMBL31268983 0.90 PPARG (0.37) CNR1PTGDR2TLR7PLA2G2APIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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