SCHEMBL31269062

SCHEMBL31269062

Cc1ccnc(Cn2c(-c3ccc(OCCC4(O)COC4)cc3Cl)nc3c(OC4(C)CC4)ncnc32)c1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PDE2A O00408 2/20 0.31
▸ PDE10A Q9Y233 2/20 0.31
▸ PIK3CD O00329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31269327 0.93 PDE2A (0.36) PDE2APDE10APIK3CD
SCHEMBL31269380 0.89 PDE2A (0.38) PDE2APDE10APIK3CD
SCHEMBL30983456 0.89 PIK3CD (0.35) PDE2APDE10APIK3CD
SCHEMBL31268935 0.88 PDE2A (0.34) PDE2APDE10APIK3CD
SCHEMBL31269061 0.87 MET (0.33) PDE2APDE10APIK3CD
SCHEMBL31268950 0.87 KCNH2 (0.32) PIK3CD
SCHEMBL30984004 0.87 KCNH2 (0.32) PIK3CD
SCHEMBL31269111 0.87 HRH4 (0.32) PIK3CD
SCHEMBL31269009 0.87 PDE2A (0.36) PDE2APDE10APIK3CD
SCHEMBL31269189 0.87 HRH4 (0.33) PDE2APIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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