Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.32 |
| ▸ | KLK1 | P06870 | 6/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.32 |
| ▸ | PARG | Q86W56 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269283 | 0.90 | PIK3CD (0.38) | PIK3CDDGAT1SMN1; SMN2CNR1CNR2 | |
| SCHEMBL31269332 | 0.89 | PIK3CD (0.36) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL30983484 | 0.89 | PIK3CD (0.36) | PIK3CDDGAT1SCN5ASCN9ACNR1 | |
| SCHEMBL30983368 | 0.89 | PIK3CD (0.36) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL31269290 | 0.88 | PIK3CD (0.37) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL31269129 | 0.88 | PIK3CD (0.35) | PIK3CDDGAT1SCN5ASCN9AALOX5AP | |
| SCHEMBL31268788 | 0.88 | PIK3CD (0.37) | PIK3CDDGAT1SCN9ACNR1CNR2 | |
| SCHEMBL31269497 | 0.87 | PIK3CD (0.35) | PIK3CDDGAT1PARGCNR1CNR2 | |
| SCHEMBL31269311 | 0.87 | PIK3CD (0.35) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL31269255 | 0.87 | PDE10A (0.38) | PIK3CDDGAT1DCTPP1CNR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |