Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269283 | 0.94 | PIK3CD (0.38) | PDE10ACNR1PIK3CDDGAT1KDM4E | |
| SCHEMBL31268757 | 0.93 | PLA2G2A (0.38) | PLA2G2AALDH1A1HSD17B10USP2MAPK1 | |
| SCHEMBL31269290 | 0.92 | PIK3CD (0.37) | PDE10ACNR1PIK3CDPLA2G2ADGAT1 | |
| SCHEMBL31269240 | 0.92 | PDE8A (0.35) | PDE10ACNR1PIK3CDPLA2G2ADGAT1 | |
| SCHEMBL31268788 | 0.91 | PIK3CD (0.37) | CNR1PIK3CDDGAT1USP2LMNA | |
| SCHEMBL31269316 | 0.90 | PIK3CD (0.35) | PDE10ACNR1PIK3CDPLA2G2ADGAT1 | |
| SCHEMBL31269133 | 0.89 | PLA2G2A (0.38) | PDE10ACNR1PIK3CDPLA2G2ADGAT1 | |
| SCHEMBL31268878 | 0.89 | PIK3CD (0.36) | PDE10ACNR1PIK3CDPLA2G2ADGAT1 | |
| SCHEMBL31269049 | 0.89 | GPR119 (0.37) | CNR1PIK3CDDGAT1DCTPP1PTGDR2 | |
| SCHEMBL31268991 | 0.89 | PIK3CD (0.36) | PDE10ACNR1PIK3CDDGAT1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |