Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269241 | 0.94 | PIK3CD (0.38) | HPGDLRRK2PIK3CDHTR1A | |
| SCHEMBL31268972 | 0.94 | PIK3CD (0.38) | PIK3CDHTR1A | |
| SCHEMBL31268886 | 0.93 | PIK3CD (0.40) | PIK3CDHTR1A | |
| SCHEMBL31269076 | 0.91 | PIK3CD (0.37) | LRRK2PIK3CDKDM4EHTR1A | |
| SCHEMBL31269121 | 0.91 | PIK3CD (0.40) | LRRK2PIK3CDHTR1A | |
| SCHEMBL31269164 | 0.90 | PIK3CD (0.40) | PIK3CDHTR1A | |
| SCHEMBL31269208 | 0.90 | PIK3CD (0.37) | PIK3CDHTR1A | |
| SCHEMBL31269085 | 0.89 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL31269279 | 0.89 | PIK3CD (0.39) | PIK3CDRAB9A | |
| SCHEMBL31268735 | 0.89 | PIK3CD (0.39) | PIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |