Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.37 |
| ▸ | HTR1A | P08908 | 7/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269164 | 0.96 | PIK3CD (0.40) | PIK3CDHTR1ADRD2DRD4DRD3 | |
| SCHEMBL31268972 | 0.92 | PIK3CD (0.38) | PIK3CDHTR1ADRD2DRD4DRD3 | |
| SCHEMBL31269241 | 0.92 | PIK3CD (0.38) | PIK3CDHTR1AADRA1ADRD2DRD4 | |
| SCHEMBL31268768 | 0.92 | PIK3CD (0.36) | PIK3CDHTR1A | |
| SCHEMBL31268887 | 0.92 | PIK3CD (0.36) | PIK3CDHTR1A | |
| SCHEMBL31269085 | 0.91 | PIK3CD (0.37) | PIK3CDKCNH2SCN5ASCN9A | |
| SCHEMBL31268769 | 0.90 | PIK3CD (0.36) | PIK3CD | |
| SCHEMBL31269121 | 0.90 | PIK3CD (0.40) | PIK3CDHTR1AKCNH2SCN5ASCN9A | |
| SCHEMBL31269199 | 0.90 | HPGD (0.40) | PIK3CDHTR1A | |
| SCHEMBL31269475 | 0.89 | PIK3CD (0.37) | PIK3CDKCNH2SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |