Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30983373 | 0.93 | DRD2 (0.39) | DRD2LTA4HTLR7MAOAMAOB | |
| SCHEMBL30983478 | 0.91 | DRD2 (0.41) | DRD2LTA4HTLR7MAOAMAOB | |
| SCHEMBL30983488 | 0.90 | DRD2 (0.40) | DRD2LTA4HTLR7MAOAMAOB | |
| SCHEMBL30983822 | 0.90 | DRD2 (0.42) | DRD2LTA4HTLR7PIK3CDMEN1 | |
| SCHEMBL30983508 | 0.90 | TLR7 (0.42) | DRD2LTA4HTLR7PIK3CDMET | |
| SCHEMBL30983412 | 0.90 | DRD2 (0.40) | DRD2LTA4HTLR7MAOAMAOB | |
| SCHEMBL30983457 | 0.88 | DRD2 (0.39) | DRD2LTA4HTLR7MAOAMAOB | |
| SCHEMBL30983540 | 0.88 | RET (0.40) | DRD2LTA4HTLR7MAOAMAOB | |
| SCHEMBL30983983 | 0.88 | MAOB (0.41) | DRD2LTA4HTLR7MAOAMAOB | |
| SCHEMBL30983890 | 0.87 | MAOB (0.40) | DRD2LTA4HTLR7MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |