Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.36 |
| ▸ | CNR1 | P21554 | 9/20 | 0.32 |
| ▸ | CNR2 | P34972 | 7/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268739 | 0.95 | NOTUM (0.39) | PIK3CDCNR1CNR2NOTUM | |
| SCHEMBL31269333 | 0.91 | PIK3CD (0.37) | PIK3CDCNR1CNR2LMNAMAPT | |
| SCHEMBL31268997 | 0.89 | PIK3CD (0.35) | PIK3CDCNR1KCNH2SCN5ASCN9A | |
| SCHEMBL31268973 | 0.88 | PIK3CD (0.38) | PIK3CDCNR1CNR2NOTUMLMNA | |
| SCHEMBL31269478 | 0.85 | SYK (0.36) | PIK3CDKCNH2SCN5ASCN9A | |
| SCHEMBL31269369 | 0.84 | PIK3CD (0.35) | PIK3CDKCNH2SCN5ASCN9A | |
| SCHEMBL31269266 | 0.84 | PIK3CD (0.35) | PIK3CDCNR1LMNAMAPTKCNH2 | |
| SCHEMBL31268824 | 0.83 | PIK3CD (0.34) | PIK3CDLMNAMAPTKCNH2SCN5A | |
| SCHEMBL31269475 | 0.83 | PIK3CD (0.37) | PIK3CDKCNH2SCN5ASCN9A | |
| SCHEMBL30983779 | 0.83 | KCNH2 (0.36) | PIK3CDCNR1KCNH2SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |