Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 13/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269210 | 0.94 | SYK (0.38) | SYKAURKBINCENPPIK3CDSCN9A | |
| SCHEMBL31269058 | 0.92 | PIK3CD (0.36) | PIK3CDSCN9AKCNH2SCN5A | |
| SCHEMBL31268793 | 0.92 | PIK3CD (0.35) | PIK3CDSCN9AKCNH2SCN5A | |
| SCHEMBL31269475 | 0.91 | PIK3CD (0.37) | PIK3CDSCN9AKCNH2SCN5A | |
| SCHEMBL31268954 | 0.91 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL31269185 | 0.91 | CNR1 (0.38) | PIK3CD | |
| SCHEMBL31269136 | 0.91 | PIK3CD (0.36) | PIK3CDSCN9AF9KCNH2SCN5A | |
| SCHEMBL31269223 | 0.90 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL31269098 | 0.90 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL31269146 | 0.90 | PIK3CD (0.35) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |