SCHEMBL3126929

SCHEMBL3126929

O=C(O)Oc1ccc(CCCN2C(=O)OCC[C@@H]2/C=C/[C@@H](O)C(F)(F)c2ccccc2)s1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGER2 P43116 8/20 0.39
PTGER4 P35408 15/20 0.39
PTGER3 P43115 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4112661 0.88 PTGER2 (0.51) PTGER2PTGER4
SCHEMBL4112667 0.88 PTGER2 (0.51) PTGER2PTGER4
SCHEMBL2212674 0.88 PTGER2 (0.51) PTGER2PTGER4
SCHEMBL2212680 0.88 PTGER2 (0.51) PTGER2PTGER4
SCHEMBL3139937 0.87 PTGER4 (0.46) PTGER2PTGER4PTGER3
SCHEMBL13871606 0.87 PTGER4 (0.42) PTGER2PTGER4PTGER3
SCHEMBL2210801 0.85 PTGER4 (0.46) PTGER2PTGER4
SCHEMBL2210793 0.85 PTGER4 (0.46) PTGER2PTGER4
SCHEMBL4792222 0.81 PTGER4 (0.52) PTGER2PTGER4PTGER3
SCHEMBL4114161 0.81 PTGER4 (0.52) PTGER2PTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1932686-B1 Pneumatic tire comprising a layered product which comprises thermoplastic resin and rubber YOKOHAMA RUBBER CO LTD (JP) 2010-07-14 EP disclosed
EP-1932686-A1 LAYERED PRODUCT COMPRISING THERMOPLASTIC RESIN AND RUBBER AND PNEUMATIC TIRE COMPRISING THE SAME The Yokohama Rubber Co., Ltd. (JP) 2008-06-18 EP disclosed